| Player | Fantasy Points | Games Played | Base Score | Consistency Score |
| 1 | Ekeler, Austin LAC RB | 320.9 | 15 | 53 | 88.33% |
| 2 | Taylor, Jonathan IND RB | 364.6 | 16 | 55 | 85.94% |
| 3 | Henry, Derrick TEN RB | 193.3 | 8 | 26 | 81.25% |
| 4 | Harris, Najee PIT RB | 291.2 | 16 | 50 | 78.13% |
| 5 | Jacobs, Josh LVR RB | 207.6 | 14 | 43 | 76.79% |
| 6 | Fournette, Leonard TBB RB | 255.6 | 14 | 42 | 75.00% |
| 7 | Kamara, Alvin NOS RB | 216.5 | 12 | 36 | 75.00% |
| 8 | Cook, Dalvin MIN RB | 201.1 | 12 | 34 | 70.83% |
| 9 | Mixon, Joe CIN RB | 289.9 | 16 | 45 | 70.31% |
| 10 | Elliott, Ezekiel DAL RB | 244.06 | 16 | 45 | 70.31% |
| 11 | Swift, D’Andre DET RB | 196.3 | 12 | 33 | 68.75% |
| 12 | McCaffrey, Christian CAR RB | 127.5 | 7 | 19 | 67.86% |
| 13 | Conner, James ARI RB | 230.4 | 14 | 37 | 66.07% |
| 14 | Harris, Damien NEP RB | 196.8 | 14 | 37 | 66.07% |
| 15 | Mitchell, Elijah SFO RB | 156.5 | 11 | 29 | 65.91% |
| 16 | Chubb, Nick CLE RB | 210.3 | 13 | 34 | 65.38% |
| 17 | Montgomery, David CHI RB | 188.1 | 13 | 34 | 65.38% |
| 18 | Patterson, Cordarrelle ATL WR | 232.4 | 15 | 39 | 65.00% |
| 19 | Jones, Aaron GBP RB | 231 | 15 | 39 | 65.00% |
| 20 | Henderson, Darrell LAR RB | 163.4 | 12 | 31 | 64.58% |
| 21 | Gibson, Antonio WAS RB | 215 | 15 | 38 | 63.33% |
| 22 | Carson, Chris SEA RB | 50.1 | 4 | 10 | 62.50% |
| 23 | White, James NEP RB | 31.2 | 3 | 7 | 58.33% |
| 24 | Robinson, James JAC RB | 177.9 | 14 | 32 | 57.14% |
| 25 | Hunt, Kareem CLE RB | 110 | 8 | 18 | 56.25% |
| 26 | Edwards-Helaire, Clyde KCC RB | 121.6 | 10 | 22 | 55.00% |
| 27 | Edmonds, Chase ARI RB | 145.3 | 12 | 26 | 54.17% |
| 28 | McKissic, J.D. WAS RB | 127.9 | 11 | 23 | 52.27% |
| 29 | Gordon, Melvin DEN RB | 182.5 | 15 | 31 | 51.67% |
| 30 | Williams, Javonte DEN RB | 198.5 | 16 | 32 | 50.00% |
| 31 | Foreman, D’Onta TEN RB | 86.5 | 8 | 16 | 50.00% |
| 32 | Hilliard, Dontrell TEN RB | 67.9 | 7 | 14 | 50.00% |
| 33 | Carter, Michael NYJ RB | 154.5 | 13 | 25 | 48.08% |
| 34 | Williams, Darrel KCC RB | 188.3 | 16 | 30 | 46.88% |
| 35 | Singletary, Devin BUF RB | 172.6 | 16 | 30 | 46.88% |
| 36 | Barkley, Saquon NYG RB | 142.7 | 13 | 23 | 44.23% |
| 37 | Dillon, AJ GBP RB | 179.9 | 16 | 28 | 43.75% |
| 38 | Reynolds, Craig DET RB | 35 | 4 | 7 | 43.75% |
| 39 | Gaskin, Myles MIA RB | 171.6 | 16 | 27 | 42.19% |
| 40 | Sanders, Miles PHI RB | 119.2 | 12 | 20 | 41.67% |
| 41 | Pollard, Tony DAL RB | 162.6 | 15 | 24 | 40.00% |
| 42 | Freeman, Devonta BAL RB | 141.9 | 15 | 24 | 40.00% |
| 43 | Booker, Devontae NYG RB | 139.5 | 15 | 24 | 40.00% |
| 44 | Davis, Mike ATL RB | 138.4 | 16 | 24 | 37.50% |
| 45 | Stevenson, Rhamondre NEP RB | 112.3 | 11 | 16 | 36.36% |
| 46 | Michel, Sony LAR RB | 142.4 | 16 | 23 | 35.94% |
| 47 | Moss, Zack BUF RB | 103.8 | 12 | 17 | 35.42% |
| 48 | Drake, Kenyan LVR RB | 102.5 | 12 | 17 | 35.42% |
| 49 | Williams, Jamaal DET RB | 113.6 | 12 | 16 | 33.33% |
| 50 | Penny, Rashaad SEA RB | 96.7 | 9 | 12 | 33.33% |
| 51 | Howard, Jordan PHI RB | 62.5 | 7 | 9 | 32.14% |
| 52 | Johnson, Ty NYJ RB | 119.1 | 15 | 19 | 31.67% |
| 53 | Hubbard, Chuba CAR RB | 126 | 16 | 20 | 31.25% |
| 54 | Johnson, Duke MIA RB | 39.9 | 4 | 5 | 31.25% |
| 55 | Mattison, Alexander MIN RB | 124.8 | 15 | 17 | 28.33% |
| 56 | Scott, Boston PHI RB | 100.6 | 16 | 18 | 28.13% |
| 57 | Ingram, Mark NOS RB | 110.6 | 14 | 15 | 26.79% |
| 58 | Breida, Matt BUF RB | 44.7 | 8 | 8 | 25.00% |
| 59 | Gainwell, Kenneth PHI RB | 106.7 | 15 | 14 | 23.33% |
| 60 | Gore, Derrick KCC RB | 53.1 | 10 | 9 | 22.50% |
| 61 | Wilson, Jeffery SFO RB | 51.5 | 8 | 7 | 21.88% |
| 62 | Burkhead, Rex HOU RB | 94.7 | 15 | 13 | 21.67% |
| 63 | Hines, Nyheim IND RB | 112.7 | 16 | 13 | 20.31% |
| 64 | Bolden, Brandon NEP RB | 103.5 | 16 | 13 | 20.31% |
| 65 | Herbert, Khalil CHI RB | 77.8 | 16 | 12 | 18.75% |
| 66 | Peterson, Adrian FA RB | 26.6 | 4 | 3 | 18.75% |
| 67 | Collins, Alex SEA RB | 70.8 | 11 | 8 | 18.18% |
| 68 | Williams, Damien CHI RB | 48.4 | 11 | 8 | 18.18% |
| 69 | Jefferson, Jermar DET RB | 25.7 | 7 | 5 | 17.86% |
| 70 | Murray, Latavius BAL RB | 82.6 | 13 | 9 | 17.31% |
| 71 | Johnson, D’Ernest CLE RB | 83.8 | 16 | 11 | 17.19% |
| 72 | Johnson, David HOU RB | 76.7 | 12 | 8 | 16.67% |
| 73 | Bernard, Giovani TBB RB | 59.1 | 12 | 8 | 16.67% |
| 74 | Jackson, Justin LAC RB | 86.2 | 13 | 8 | 15.38% |
| 75 | Bell, Le’Veon FA RB | 29.6 | 7 | 4 | 14.29% |
| 76 | Dallas, DeeJay SEA RB | 60 | 16 | 9 | 14.06% |
| 77 | Barber, Peyton LVR RB | 49.9 | 9 | 5 | 13.89% |
| 78 | Jones, Ronald TBB RB | 83.2 | 16 | 8 | 12.50% |
| 79 | Hyde, Carlos JAC RB | 49.8 | 12 | 6 | 12.50% |
| 80 | Williams, Ty’Son BAL RB | 41.5 | 12 | 6 | 12.50% |
| 81 | Perine, Samaje CIN RB | 83.2 | 15 | 7 | 11.67% |
| 82 | Homer, Travis SEA RB | 58.1 | 13 | 6 | 11.54% |
| 83 | Abdullah, Ameer CAR RB | 72.3 | 16 | 7 | 10.94% |
| 84 | McNichols, Jeremy FA RB | 73.6 | 14 | 6 | 10.71% |
| 85 | Juszczyk, Kyle SFO RB | 73.8 | 16 | 6 | 9.38% |
| 86 | Ogunbowale, Dare JAC RB | 41.6 | 16 | 6 | 9.38% |
| 87 | Sermon, Trey SFO RB | 28.3 | 9 | 3 | 8.33% |
| 88 | Patterson, Jaret WAS RB | 50.4 | 16 | 5 | 7.81% |
| 89 | Lindsay, Phillip MIA RB | 41.4 | 13 | 4 | 7.69% |
| 90 | Coleman, Tevin NYJ RB | 50.9 | 10 | 3 | 7.50% |
| 91 | Hasty, JaMycal SFO RB | 47 | 10 | 3 | 7.50% |
| 92 | Evans, Chris CIN RB | 33.9 | 13 | 3 | 5.77% |
| 93 | Montgomery, Ty NOS RB | 28.8 | 13 | 3 | 5.77% |
| 94 | Freeman, Royce HOU RB | 34.6 | 14 | 3 | 5.36% |
| 95 | Felton, Demetric CLE RB | 40.1 | 15 | 3 | 5.00% |
| 96 | Penny, Elijhaa NYG RB | 35.9 | 16 | 3 | 4.69% |
| 97 | Igwebuike, Godwin DET RB | 30.8 | 16 | 3 | 4.69% |
| 98 | Ahmed, Salvon MIA RB | 38.6 | 12 | 0 | 0.00% |
| 99 | Ham, C.J. MIN RB | 31.2 | 16 | 0 | 0.00% |
| 100 | Ingold, Alec LVR RB | 24.6 | 9 | 0 | 0.00% |
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